human SYNM shRNA silencing AAV

Cat. No: shAAV-232489

Availability: 4-5 weeks

Name: AAV-h-SYNM-shRNA

This is an AAV expressing shRNA for silencing of Human SYNM.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYNM
Gene Name: synemin
Gene ID: 23336
Gene Synonyms: DMN; SYN
ORF Size: 4698 bp
RefSeq#: NM_015286
Gene Description: SYNM is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.
HGNC ID: HGNC:24466