human LIMS1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-232164
Availability:
4-5 weeks
Name:
AAV-h-LIMS1-shRNA
This is an AAV expressing shRNA for silencing of Human LIMS1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- LIMS1
- Gene Name
- LIM zinc finger domain containing 1
- Gene ID
- 3987
- Gene Synonyms
- PINCH; PINCH-1; PINCH1
- ORF Size
- 978 bp
- RefSeq#
- NM_004987
- Gene Description
- LIMS1 is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.597715
- HGNC ID
- HGNC:6616
Related Products
Product | Cat No. |
---|---|
AAV-h-LIMS1 | AAV-232164 |
AAV-m-LIMS1 | AAV-263459 |
Ad-h-LIMS1 | ADV-232164 |
Ad-m-LIMS1 | ADV-263459 |
AAV-m-LIMS1-shRNA | shAAV-263459 |
Ad-h-LIMS1-shRNA | shADV-232164 |
Ad-m-LIMS1-shRNA | shADV-263459 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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