human LIMS1 Over-expression AAV

Name 
AAV-h-LIMS1
Cat No 
AAV-232164
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LIMS1.

AAV-232164
AAV-h-LIMS1

Ready-to-use AAV expressing Human LIMS1 (LIM zinc finger domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PINCH; PINCH-1; PINCH1
Description (Vector)
LIMS1 is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
3987
Gene Name (Vector)
LIM zinc finger domain containing 1
Gene Symbol
LIMS1
HGNC ID
HGNC:6616
ORF Size (aa)
978
ORF Size (bp)
978 bp
RefSeq ID
NM_004987
RefSeq Synonyms
NM_004987, NM_001193488, NM_001193485, NM_001193484, NM_001193483, NM_001193482, BC005341,
Species
human
UniGene ID
Hs.597715

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.