human TRIM3 shRNA silencing AAV

Cat. No: shAAV-226423

Availability: 4-5 weeks

Name: AAV-h-TRIM3-shRNA

This is an AAV expressing shRNA for silencing of Human TRIM3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TRIM3
Gene Name: tripartite motif containing 3
Gene ID: 10612
Gene Synonyms: BERP; HAC1; RNF22; RNF97
ORF Size: 2235 bp
RefSeq#: NM_006458
Gene Description: TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.
UniGene ID: Hs.591992
HGNC ID: HGNC:10064