human TIPRL shRNA silencing AAV

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Human

Gene Symbol

TIPRL

Gene Name

TOR signaling pathway regulator

Gene ID

261726

Gene Synonyms

TIP; TIP41; TIPRL1

ORF Size

537 bp

RefSeq#

NM_152902

Gene Description

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 (PubMed 17384681)).(supplied by OMIM, Nov 2010)

UniGene ID

Hs.209431

HGNC ID

HGNC:30231