human SYT5 shRNA silencing AAV

Cat. No: shAAV-224856

Availability: 4-5 weeks

Name: AAV-h-SYT5-shRNA

This is an AAV expressing shRNA for silencing of Human SYT5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYT5
Gene Name: synaptotagmin 5
Gene ID: 6861
ORF Size: 1161 bp
RefSeq#: NM_003180
Gene Description: Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 (PubMed 7597049)).(supplied by OMIM, Feb 2011)
UniGene ID: Hs.631566
HGNC ID: HGNC:11513