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human BRD9 shRNA silencing AAV

Name 
AAV-h-BRD9-shRNA
Cat No 
shAAV-202262
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BRD9.

shAAV-202262
AAV-h-BRD9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BRD9 (bromodomain containing 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bromodomain-containing protein 9; LAVS3040; PRO9856; rhabdomyosarcoma antigen MU-RMS-40.8; sarcoma antigen NY-SAR-29
Description (eCommerce)
BRD9 plays a role in chromatin remodeling and regulation of transcription. It acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. BRD9 is a component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. BRD9 also orchestrates RAD51-RAD54 complex formation and thereby plays a role in homologous recombination [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H8M2].
Gene ID
65980
Gene Name (eCommerce)
bromodomain containing 9
Gene Name (Vector)
bromodomain containing 9
Gene Symbol
BRD9
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
Protein Name (eCommerce)
Bromodomain-containing protein 9
RefSeq ID
NM_023924
RefSeq Synonyms
NM_023924, NM_001317951, NM_001009877, BC041590,
Research Areas
Chromatin Remodeling,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
BRD9 plays a role in chromatin remodeling and regulation of transcription. It acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. BRD9 is a component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. BRD9 also orchestrates RAD51-RAD54 complex formation and thereby plays a role in homologous recombination [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H8M2].
UniGene ID
Hs.449278
UniProt ID (eCommerce)
Q9H8M2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.