human SNRPB shRNA silencing AAV

Cat. No: shAAV-223877

Availability: 4-5 weeks

Name: AAV-h-SNRPB-shRNA

This is an AAV expressing shRNA for silencing of Human SNRPB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SNRPB
Gene Name: small nuclear ribonucleoprotein polypeptides B and B1
Gene ID: 6628
Gene Synonyms: CCMS; COD; Sm-B/B'; SmB/B'; SmB/SmB'; snRNP-B; SNRPB1
ORF Size: 696 bp
RefSeq#: NM_198216
Gene Description: SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
UniGene ID: Hs.83753
HGNC ID: HGNC:11153