human SNRPB Over-expression AAV

Name
AAV-h-SNRPB

Cat No
AAV-223877

Availability
4-5 weeks

This is an AAV expressing Human SNRPB.

AAV-223877

AAV-h-SNRPB

Ready-to-use AAV expressing Human SNRPB (small nuclear ribonucleoprotein polypeptides B and B1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CCMS; COD; Sm-B/B'; SmB/B'; SmB/SmB'; snRNP-B; SNRPB1

Description (Vector)

SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

Gene ID

6628

Gene Name (Vector)

small nuclear ribonucleoprotein polypeptides B and B1

Gene Symbol

SNRPB

HGNC ID

HGNC:11153

ORF Size (aa)

696

RefSeq ID

NM_198216

RefSeq Synonyms

NM_198216, NM_003091, BC080516,

Species

human

UniGene ID

Hs.83753

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.