human SLC5A7 shRNA silencing AAV

Cat. No: shAAV-223546

Availability: 6-8 weeks

Name: AAV-h-SLC5A7-shRNA

This is an AAV expressing shRNA for silencing of Human SLC5A7.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC5A7
Gene Name: solute carrier family 5 member 7
Gene ID: 60482
Gene Synonyms: CHT; CHT1; CMS20; HMN7A
ORF Size: 1002 bp
RefSeq#: NM_021815
Gene Description: Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 (PubMed 11027560)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.287758
HGNC ID: HGNC:14025