human SCN10A shRNA silencing AAV

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Human

Gene Symbol

SCN10A

Gene Name

sodium voltage-gated channel alpha subunit 10

Gene ID

6336

Gene Synonyms

FEPS2; hPN3; Nav1.8; PN3; SNS

ORF Size

5868 bp

RefSeq#

NM_006514

Gene Description

SCN10A is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy.

UniGene ID

Hs.250443

HGNC ID

HGNC:10582