human SBDS shRNA silencing AAV

Cat. No: shAAV-222279

Availability: 4-5 weeks

Name: AAV-h-SBDS-shRNA

This is an AAV expressing shRNA for silencing of Human SBDS.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SBDS
Gene Name: SBDS ribosome assembly guanine nucleotide exchange factor
Gene ID: 51119
Gene Synonyms: CGI-97; SDS; SWDS
ORF Size: 753 bp
RefSeq#: NM_016038
Gene Description: SBDS encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. SBDS has a closely linked pseudogene that is distally located.
UniGene ID: Hs.110445
HGNC ID: HGNC:19440