human S100A12 shRNA silencing AAV

Cat. No: shAAV-222158

Availability: 6-8 weeks

Name: AAV-h-S100A12-shRNA

This is an AAV expressing shRNA for silencing of Human S100A12.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: S100A12
Gene Name: S100 calcium binding protein A12
Gene ID: 6283
Gene Synonyms: CAAF1; CAGC; CGRP; ENRAGE; MRP-6; MRP6; p6
ORF Size: 279 bp
RefSeq#: NM_005621
Gene Description: S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities.
UniGene ID: Hs.19413
HGNC ID: HGNC:10489