human RGS9BP shRNA silencing AAV

Name
AAV-h-RGS9BP-shRNA

Cat No
shAAV-221142

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RGS9BP.

shAAV-221142

AAV-h-RGS9BP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RGS9BP (regulator of G-protein signaling 9 binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PERRS; R9AP; RGS9

Description (Vector)

RGS9BP functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia.

Gene ID

388531

Gene Name (Vector)

regulator of G-protein signaling 9 binding protein

Gene Symbol

RGS9BP

HGNC ID

HGNC:30304

ORF Size (aa)

708

RefSeq ID

NM_207391

RefSeq Synonyms

NM_207391, BC172343,

Species

human

UniGene ID

Hs.528491

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.