human RGS3 shRNA silencing AAV

Cat. No: shAAV-221127

Availability: 6-8 weeks

Name: AAV-h-RGS3-shRNA

This is an AAV expressing shRNA for silencing of Human RGS3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RGS3
Gene Name: regulator of G-protein signaling 3
Gene ID: 5998
Gene Synonyms: C2PA; RGP3
ORF Size: 2754 bp
RefSeq#: NM_144489
Gene Description: RGS3 encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
UniGene ID: Hs.494875
HGNC ID: HGNC:9999