human RENBP shRNA silencing AAV

Name
AAV-h-RENBP-shRNA

Cat No
shAAV-221006

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RENBP.

shAAV-221006

AAV-h-RENBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RENBP (renin binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RBP; RNBP

Description (Vector)

The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature.

Gene ID

5973

Gene Name (Vector)

renin binding protein

Gene Symbol

RENBP

HGNC ID

HGNC:9959

ORF Size (aa)

1254

ORF Size (bp)

1254 bp

RefSeq ID

NM_002910

RefSeq Synonyms

NM_002910, BC015558,

Species

human

UniGene ID

Hs.158331

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.