human RENBP shRNA silencing AAV

Cat. No: shAAV-221006

Availability: 6-8 weeks

Name: AAV-h-RENBP-shRNA

This is an AAV expressing shRNA for silencing of Human RENBP.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RENBP
Gene Name: renin binding protein
Gene ID: 5973
Gene Synonyms: RBP; RNBP
ORF Size: 1254 bp
RefSeq#: NM_002910
Gene Description: The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature.
UniGene ID: Hs.158331
HGNC ID: HGNC:9959