human PRSS7 shRNA silencing AAV

Name 
AAV-h-PRSS7-shRNA
Cat No 
shAAV-220034
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TMPRSS15.

shAAV-220034
AAV-h-PRSS7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMPRSS15 (transmembrane protease, serine 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ENTK; PRSS7
Description (Vector)
TMPRSS15 encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.
Gene ID
5651
Gene Name (Vector)
transmembrane protease, serine 15
Gene Symbol
TMPRSS15
HGNC ID
HGNC:9490
ORF Size (aa)
3060
ORF Size (bp)
3060 bp
RefSeq ID
NM_002772
RefSeq Synonyms
NM_002772, BC111749,
Species
human
UniGene ID
Hs.149473

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.