human LSM1 shRNA silencing AAV

Cat. No: shAAV-214630

Availability: 4-5 weeks

Name: AAV-h-LSM1-shRNA

This is an AAV expressing shRNA for silencing of Human LSM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: LSM1
Gene Name: LSM1 homolog, mRNA degradation associated
Gene ID: 27257
Gene Synonyms: CASM; YJL124C
ORF Size: 402 bp
RefSeq#: NM_014462
Gene Description: LSM1 encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
UniGene ID: Hs.425311
HGNC ID: HGNC:20472