human LSM1 Over-expression AAV

Name 
AAV-h-LSM1
Cat No 
AAV-214630
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LSM1.

AAV-214630
AAV-h-LSM1

Ready-to-use AAV expressing Human LSM1 (LSM1 homolog, mRNA degradation associated). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CASM; YJL124C
Description (Vector)
LSM1 encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Gene ID
27257
Gene Name (Vector)
LSM1 homolog, mRNA degradation associated
Gene Symbol
LSM1
HGNC ID
HGNC:20472
ORF Size (aa)
402
RefSeq ID
NM_014462
RefSeq Synonyms
NM_014462, BC001767,
Species
human
UniGene ID
Hs.425311

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.