human KRT84 shRNA silencing AAV

Cat. No: shAAV-213466

Availability: 6-8 weeks

Name: AAV-h-KRT84-shRNA

This is an AAV expressing shRNA for silencing of Human KRT84.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KRT84
Gene Name: keratin 84
Gene ID: 3890
Gene Synonyms: HB4; KRTHB4
ORF Size: 1803 bp
RefSeq#: NM_033045
Gene Description: KRT84 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin is contained primarily in the filiform tongue papilla, among other hair keratins.
UniGene ID: Hs.272336
HGNC ID: HGNC:6461