human IST1 shRNA silencing AAV

Cat. No: shAAV-212887

Availability: 6-8 weeks

Name: AAV-h-IST1-shRNA

This is an AAV expressing shRNA for silencing of Human IST1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IST1
Gene Name: IST1, ESCRT-III associated factor
Gene ID: 9798
Gene Synonyms: OLC1
ORF Size: 1083 bp
RefSeq#: NM_014761
Gene Description: IST1 encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.232194
HGNC ID: HGNC:28977