human KCNB1 shRNA silencing AAV

Cat. No: shAAV-212668

Availability: 6-8 weeks

Name: AAV-h-KCNB1-shRNA

This is an AAV expressing shRNA for silencing of Human KCNB1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNB1
Gene Name: potassium voltage-gated channel subfamily B member 1
Gene ID: 3745
Gene Synonyms: DRK1; Kv2.1
ORF Size: 2574 bp
RefSeq#: NM_004975
Gene Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.
UniGene ID: Hs.84244
HGNC ID: HGNC:6231