human FOLR3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FOLR3.
shAAV-209220
AAV-h-FOLR3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FOLR3 (folate receptor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FR-G; FR-gamma; gamma-hFR
Description (Vector)
FOLR3 encodes a member of the folate receptor (FOLR) family, members of which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR3 includes two polymorphic variants; the shorter one has two base deletion in the CDS, resulting in a truncated polypeptide, compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively.
Gene ID
2352
Gene Name (Vector)
folate receptor 3
Gene Symbol
FOLR3
HGNC ID
HGNC:3795
ORF Size (aa)
738
ORF Size (bp)
738 bp
RefSeq ID
NM_000804
RefSeq Synonyms
NM_001318045, NM_000804, BC148785, BC141505,
Species
human
UniGene ID
Hs.352
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.