human FGF20 shRNA silencing AAV

Cat. No: shAAV-208962

Availability: 6-8 weeks

Name: AAV-h-FGF20-shRNA

This is an AAV expressing shRNA for silencing of Human FGF20.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FGF20
Gene Name: fibroblast growth factor 20
Gene ID: 26281
Gene Synonyms: FGF-20; RHDA2
ORF Size: 636 bp
RefSeq#: NM_019851
Gene Description: FGF20 is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
UniGene ID: Hs.199905
HGNC ID: HGNC:3677