human ERBB2IP shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-208042
Availability:
4-5 weeks
Name:
AAV-h-ERBB2IP-shRNA
This is an AAV expressing shRNA for silencing of Human ERBIN.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ERBIN
- Gene Name
- erbb2 interacting protein
- Gene ID
- 55914
- Gene Synonyms
- ERBB2IP; HEL-S-78; LAP2
- ORF Size
- 4104 bp
- RefSeq#
- NM_018695
- Gene Description
- ERBB2IP is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniGene ID
- Hs.591774
- HGNC ID
- HGNC:15842
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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