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human ERBB2IP Adenovirus

Name 
Ad-h-ERBB2IP
Cat No 
ADV-208042
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ERBB2IP.

ADV-208042
Ad-h-ERBB2IP

Ready-to-use Adenovirus expressing Human ERBIN (erbb2 interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
densin-180-like protein; epididymis secretory protein Li 78; Erbb2-interacting protein; ERBB2IP; erbin; HEL-S-78; LAP2; protein LAP2
Description (eCommerce)
Erbin (Erbb2-interacting protein) is a member of the leucine-rich repeat and PDZ domain (LAP) family. Erbin contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction [taken from NCBI Entrez Gene (Gene ID: 55914)].
Description (Vector)
ERBB2IP is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
55914
Gene Name (eCommerce)
erbb2 interacting protein
Gene Name (Vector)
erbb2 interacting protein
Gene Symbol
ERBIN
HGNC ID
HGNC:15842
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4104
ORF Size (bp)
4104 bp
Protein Name (eCommerce)
Protein LAP2
RefSeq ID
NM_018695
RefSeq Synonyms
NM_018695, NM_001253701, NM_001253699, NM_001253698, NM_001253697, NM_001006600, BC144075, BC126464, BC115015, BC115012,
Research Areas
Cell Biology,Cell Cycle,Cytoskeleton,EGFR Signaling,Immunology,Signal Transduction,T-cell Receptor Signaling,Translational Control
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,immunology,genetics,transcription_translation
Species
human
Target Sentence
Erbin (Erbb2-interacting protein) is a member of the leucine-rich repeat and PDZ domain (LAP) family. Erbin contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction [taken from NCBI Entrez Gene (Gene ID: 55914)].
UniGene ID
Hs.591774
UniProt ID (eCommerce)
Q96RT1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.