human EPO shRNA silencing AAV

Name
AAV-h-EPO-shRNA

Cat No
shAAV-208016

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human EPO.

shAAV-208016

AAV-h-EPO-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EPO (erythropoietin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EP; MVCD2

Description (Vector)

EPO is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.

Gene ID

2056

Gene Name (Vector)

erythropoietin

Gene Symbol

EPO

HGNC ID

HGNC:3415

ORF Size (aa)

579

ORF Size (bp)

579 bp

RefSeq ID

NM_000799

RefSeq Synonyms

NM_000799, BC143225, BC111937, BC093628,

Species

human

UniGene ID

Hs.2303

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.