human BFSP1 shRNA silencing AAV

Cat. No: shAAV-202117

Availability: 6-8 weeks

Name: AAV-h-BFSP1-shRNA

This is an AAV expressing shRNA for silencing of Human BFSP1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BFSP1
Gene Name: beaded filament structural protein 1
Gene ID: 631
Gene Synonyms: CP115; CP94; CTRCT33; LIFL-H
ORF Size: 1623 bp
RefSeq#: NM_001195
Gene Description: More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.129702
HGNC ID: HGNC:1040