rat DOK1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-294027
Availability:
3-5 weeks
Name:
AAV-r-DOK1
This is an AAV expressing Rat Dok1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Dok1
- Gene Name
- docking protein 1
- Gene ID
- 312477
- Gene Synonyms
- Dok-1
- ORF Size
- 1443 bp
- RefSeq#
- BC097972
- Gene Description
- DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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