rat MFGE8 Over-expression AAV

Cat. No: AAV-292151

Availability: 3-5 weeks

Name: AAV-r-MFGE8

This is an AAV expressing Rat Mfge8.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Mfge8
Gene Name: milk fat globule-EGF factor 8 protein
Gene ID: 25277
Gene Synonyms: AGS; MFGME8; MFGMP-E8; OAcGD3S
ORF Size: 1284 bp
RefSeq#: BC085754
Gene Description: Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication|Function: Medin is the main constituent of aortic medial amyloid.