rat TRAF4AF1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-292019
Availability:
3-5 weeks
Name:
AAV-r-TRAF4AF1
This is an AAV expressing Rat Knstrn.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Knstrn
- Gene Name
- kinetochore-localized astrin/SPAG5 binding protein
- Gene ID
- 311325
- Gene Synonyms
- C15orf23; SKAP; Traf4af1
- ORF Size
- 939 bp
- RefSeq#
- BC079438
- Gene Description
- Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
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