rat TIFA Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-291871
Availability:
3-5 weeks
Name:
AAV-r-TIFA
This is an AAV expressing Rat Tifa.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Tifa
- Gene Name
- TRAF-interacting protein with forkhead-associated domain
- Gene ID
- 310877
- Gene Synonyms
- Ab2-389; T2bp
- ORF Size
- 558 bp
- RefSeq#
- BC083765
- Gene Description
- Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
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