mouse CNTN1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-280645
Availability:
3-5 weeks
Name:
AAV-m-CNTN1
This is an AAV expressing Mouse Cntn1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Cntn1
- Gene Name
- contactin 1
- Gene ID
- 12805
- Gene Synonyms
- AW495098; CNTN; F3cam; usl
- ORF Size
- 3063 bp
- RefSeq#
- BC066864
- Gene Description
- Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).
- UniGene ID
- Mm.470343
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