mouse TNFRSF11B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-274691
Availability:
Immediate
Name:
AAV-m-TNFRSF11B
This is an AAV expressing Mouse Tnfrsf11b.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Tnfrsf11b
- Gene Name
- tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
- Gene ID
- 18383
- Gene Synonyms
- OCIF; Opg; TR1
- ORF Size
- 1206 bp
- RefSeq#
- BC049782
- Gene Description
- Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
- UniGene ID
- Mm.15383
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