mouse TFB2M Over-expression AAV

Cat. No: AAV-274081

Availability: 3-5 weeks

Name: AAV-m-TFB2M

This is an AAV expressing Mouse Tfb2m.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tfb2m
Gene Name: transcription factor B2, mitochondrial
Gene ID: 15278
Gene Synonyms: Hkp1
ORF Size: 1191 bp
RefSeq#: BC138836
Gene Description: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
UniGene ID: Mm.293529