mouse SMO Over-expression AAV

Cat. No: AAV-272652

Availability: 3-5 weeks

Name: AAV-m-SMO

This is an AAV expressing Mouse Smo.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Smo
Gene Name: smoothened, frizzled class receptor
Gene ID: 319757
Gene Synonyms: bnb; E130215L21Rik; Smoh; smoothened
ORF Size: 1320 bp
RefSeq#: BC048091
Gene Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
UniGene ID: Mm.29279