mouse PPP1R3B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-269215
Availability:
Immediate
Name:
AAV-m-PPP1R3B
This is an AAV expressing Mouse Ppp1r3b.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ppp1r3b
- Gene Name
- protein phosphatase 1, regulatory (inhibitor) subunit 3B
- Gene ID
- 244416
- Gene Synonyms
- 6430576E21; AW821953; GL; PTG
- ORF Size
- 855 bp
- RefSeq#
- BC079666
- Gene Description
- Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).
- UniGene ID
- Mm.247126
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