mouse PIAS3 Over-expression AAV

Cat. No: AAV-268598

Availability: 3-5 weeks

Name: AAV-m-PIAS3

This is an AAV expressing Mouse Pias3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pias3
Gene Name: protein inhibitor of activated STAT 3
Gene ID: 229615
Gene Synonyms: Pias3l
ORF Size: 1887 bp
RefSeq#: BC051252
Gene Description: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.
UniGene ID: Mm.1635