mouse PAG1 Over-expression AAV

Cat. No: AAV-268004

Availability: 3-5 weeks

Name: AAV-m-PAG1

This is an AAV expressing Mouse Pag1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pag1
Gene Name: phosphoprotein associated with glycosphingolipid microdomains 1
Gene ID: 94212
Gene Synonyms: Cbp; F730007C19Rik; Pag
ORF Size: 1290 bp
RefSeq#: BC145763
Gene Description: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
UniGene ID: Mm.214484