mouse MCM4 Over-expression AAV

Cat. No: AAV-264375

Availability: 3-5 weeks

Name: AAV-m-MCM4

This is an AAV expressing Mouse Mcm4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mcm4
Gene Name: minichromosome maintenance complex component 4
Gene ID: 17217
Gene Synonyms: 19G; AI325074; AU045576; Cdc21; mcdc21; Mcmd4; mKIAA4003
ORF Size: 2589 bp
RefSeq#: BC013094
Gene Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
UniGene ID: Mm.472867