mouse MAEL Over-expression AAV

Cat. No: AAV-264079

Availability: 3-5 weeks

Name: AAV-m-MAEL

This is an AAV expressing Mouse Mael.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mael
Gene Name: maelstrom spermatogenic transposon silencer
Gene ID: 98558
Gene Synonyms: 4933405K18Rik; AU019877
ORF Size: 1305 bp
RefSeq#: BC050800
Gene Description: Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).
UniGene ID: Mm.26189