mouse KLF4 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-262870
Availability:
Immediate
Name:
AAV-m-KLF4
This is an AAV expressing Mouse Klf4.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Klf4
- Gene Name
- Kruppel-like factor 4 (gut)
- Gene ID
- 16600
- Gene Synonyms
- EZF; Gklf; Zie
- ORF Size
- 1425 bp
- RefSeq#
- BC010301
- Gene Description
- Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
- UniGene ID
- Mm.4325
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