mouse CTDSP1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-256294
Availability:
3-5 weeks
Name:
AAV-m-CTDSP1
This is an AAV expressing Mouse Ctdsp1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ctdsp1
- Gene Name
- CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
- Gene ID
- 227292
- Gene Synonyms
- GIP; Nif3; NLIIF; SCP1
- ORF Size
- 786 bp
- RefSeq#
- BC049184
- Gene Description
- Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
- UniGene ID
- Mm.165042
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