mouse 2610301G19RIK Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-250817
Availability:
3-5 weeks
Name:
AAV-m-2610301G19RIK
This is an AAV expressing Mouse Ccar2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ccar2
- Gene Name
- cell cycle activator and apoptosis regulator 2
- Gene ID
- 219158
- Gene Synonyms
- 2610301G19Rik; Dbc1; mKIAA1967
- ORF Size
- 2769 bp
- RefSeq#
- BC021475
- Gene Description
- Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.
- UniGene ID
- Mm.218284
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