human MUTED Over-expression AAV

Cat. No: AAV-232490

Availability: 3-5 weeks

Name: AAV-h-MUTED

This is an AAV expressing Human BLOC1S5.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BLOC1S5
Gene Name: biogenesis of lysosomal organelles complex 1 subunit 5
Gene ID: 63915
Gene Synonyms: BLOS5; MU; MUTED
ORF Size: 564 bp
RefSeq#: BC119644
Gene Description: BLOC1S5 encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
UniGene ID: Hs.719272
HGNC ID: HGNC:18561