human ACO2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-230719
Availability:
3-5 weeks
Name:
AAV-h-ACO2
This is an AAV expressing Human ACO2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ACO2
- Gene Name
- aconitase 2
- Gene ID
- 50
- Gene Synonyms
- ACONM; HEL-S-284; ICRD; OCA8; OPA9
- ORF Size
- 2343 bp
- RefSeq#
- BC026196
- Gene Description
- ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
- UniGene ID
- Hs.643610
- HGNC ID
- HGNC:118
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