human XPC Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227906
Availability:
3-5 weeks
Name:
AAV-h-XPC
This is an AAV expressing Human XPC.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- XPC
- Gene Name
- XPC complex subunit, DNA damage recognition and repair factor
- Gene ID
- 7508
- Gene Synonyms
- p125; RAD4; XP3; XPCC
- ORF Size
- 2823 bp
- RefSeq#
- BC016620
- Gene Description
- XPC encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
- UniGene ID
- Hs.475538
- HGNC ID
- HGNC:12816
Related Products
Product | Cat No. |
---|---|
AAV-m-XPC | AAV-276402 |
Ad-h-XPC | ADV-227906 |
Ad-m-XPC | ADV-276402 |
AAV-h-XPC-shRNA | shAAV-227906 |
AAV-m-XPC-shRNA | shAAV-276402 |
Ad-h-XPC-shRNA | shADV-227906 |
Ad-m-XPC-shRNA | shADV-276402 |
Control Products
Vector Biolabs
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Malvern, PA 19355
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