human UGT2A1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227143
Availability:
3-5 weeks
Name:
AAV-h-UGT2A1
This is an AAV expressing Human UGT2A1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- UGT2A1
- Gene Name
- UDP glucuronosyltransferase family 2 member A1 complex locus
- Gene ID
- 10941
- Gene Synonyms
- UDPGT2A1
- ORF Size
- 1584 bp
- RefSeq#
- BC157012
- Gene Description
- UGT2A1 belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.225950
- HGNC ID
- HGNC:12542
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