human UBQLN1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227069
Availability:
3-5 weeks
Name:
AAV-h-UBQLN1
This is an AAV expressing Human UBQLN1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- UBQLN1
- Gene Name
- ubiquilin 1
- Gene ID
- 29979
- Gene Synonyms
- DA41; DSK2; PLIC-1; UBQN; XDRP1
- ORF Size
- 1686 bp
- RefSeq#
- BC010066
- Gene Description
- UBQLN1 encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.9589
- HGNC ID
- HGNC:12508
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Control Products
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