human SGSH Over-expression AAV

Cat. No: AAV-222869

Availability: 3-5 weeks

Name: AAV-h-SGSH

This is an AAV expressing Human SGSH.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SGSH
Gene Name: N-sulfoglucosamine sulfohydrolase
Gene ID: 6448
Gene Synonyms: HSS; MPS3A; SFMD
ORF Size: 1509 bp
RefSeq#: BC047318
Gene Description: SGSH encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
UniGene ID: Hs.31074
HGNC ID: HGNC:10818